Question 1

If the following oligonucleotide of double-stranded DNA were transcribed, what would be the sequence of the RNA? 5TGCTAGCTA3
3ACGATCGAT5

Accepted Answer

A)   5UGCUAGCUA3
B)   5ACGAUCGAU3
C)   3ACGATCGAT5
D)   3ACGAUCGAU5E) B) and C)
F) A) and C)

Question 2

Multiple products are generated from the same gene by what mechanism?

Accepted Answer

A)   Alternative splicing
B)   Polyadenylation
C)   CappingD) All of the above
E) B) and C) A

Question 3

What mechanism may explain the difference in symptoms in Prader-Willi and Angelman syndromes?

Accepted Answer

A)   Genomic imprinting
B)   Alternative splicing
C)   Genetic recombination
D)   CappingE) All of the above
F) B) and D)

Question 4

The loop of transfer RNA that interacts with the codon on mRNA in translation is called the:

Accepted Answer

A)   D loop
B)   TC loop
C)   Variable loop
D)   Anticodon loopE) C) and D)
F) A) and D) D

Question 5

Which of the following is required for termination of transcription in bacteria?

Accepted Answer

A)   DNA polymerase
B)   Sigma
C)   Rho
D)   PolyA signalE) A) and B)
F) None of the above

Question 6

Synthesis of RNA guided by a DNA template is:

Accepted Answer

A)   Translation
B)   DNA replication
C)   Transcription
D)   Reverse transcriptionE) A) and D)
F) C) and D)

Question 7

The most frequently methylated base in vertebrates is:

Accepted Answer

A)   Adenine
B)   Cytosine
C)   Guanine
D)   ThymineE) A) and B)
F) B) and C)

Question 8

DNA sequences that are involved in the regulation of gene expression are called:

Accepted Answer

A)   Cis factors
B)   Trans factors
C)   Inducers
D)   RepressorsE) A) and B)
F) A) and C)

Question 9

Which of the following is involved in termination of transcription in eukaryotes?

Accepted Answer

A)   RNA polymerase
B)   Sigma
C)   Rho
D)   PolyA signalE) A) and B)
F) A) and C)

Question 10

In the lactose operon, which of the following configurations would result in gene expression?

Accepted Answer

A)   Promoter +, Operator +, Repressor +, no inducer present
B)   Promoter -, Operator +, Repressor +, no inducer present
C)   Promoter -, Operator -, Repressor +, inducer present
D)   Promoter +, Operator +, Repressor -, no inducer presentE) None of the above
F) B) and C) D

Question 11

The large ribosome subunit in prokaryotes consists of ribosomal proteins and:

Accepted Answer

A)   16S rRNA
B)   18S rRNA
C)   23S rRNA and 5S rRNA
D)   28S rRNA, 5S rRNA, and 5.8S rRNAE) B) and C)
F) A) and B)

Question 12

In transcription, what is the starting material, the ending material, and the major enzyme that catalyzes the process?

Accepted Answer

A)   DNA, RNA, DNA polymerase
B)   RNA, protein, peptidyl transferase
C)   RNA, DNA, reverse transcriptase
D)   DNA, RNA, RNA polymeraseE) A) and B)
F) B) and C)

Question 13

RNA is degraded by:

Accepted Answer

A)   Helicases
B)   Polymerases
C)   Ribonucleases
D)   MethylasesE) None of the above
F) B) and C)

Question 14

What is the secondary structure of transfer RNA?

Accepted Answer

A)   Cruciform, or inverted L
B)   Hairpin
C)   Triple helix, or triplex
D)   Ring, or inverted CE) B) and D)
F) B) and C)

Question 15

Thalassemias arise from changes in what part of the beta-globin gene?

Accepted Answer

A)   3untranslated region
B)   PolyA tail
C)   Splice recognition site
D)   Ribosome binding siteE) B) and C)
F) A) and B)

Question 16

When gene expression is regulated by mechanisms other than the interaction of cis elements and trans factors, the regulation is called:

Accepted Answer

A)   Induction
B)   Epigenetics
C)   Attenuation
D)   Combinatorial controlE) A) and C)
F) None of the above

Question 17

Which of the following enzymes performs transcription in bacteria?

Accepted Answer

A)   RNA-dependent DNA polymerase
B)   DNA-dependent RNA polymerase
C)   DNA-dependent DNA polymerase
D)   RNA-dependent RNA polymeraseE) All of the above
F) A) and C)

Question 18

Which of the following would prevent transcription of the lactose operon?

Accepted Answer

A)   Loss of promoter
B)   Presence of inducer
C)   Loss of the repressor protein
D)   RNA polymerase binding to the promoterE) B) and D)
F) A) and D)

Question 19

Genomic imprinting is accomplished primarily through:

Accepted Answer

A)   Methylation
B)   Acetylation
C)   Transcription
D)   Cis and trans factor interactionsE) C) and D)
F) A) and B)

Question 20

Which of the following types of RNA is directly involved in removing introns from RNA in eukaryotes?

Accepted Answer

A)   Micro
B)   Transfer
C)   Small nuclear
D)   Small interferingE) A) and B)
F) C) and D)

Exam 2: RNA

If the following oligonucleotide of double-stranded DNA were transcribed, what would be the sequence of the RNA? 5TGCTAGCTA3 3ACGATCGAT5

Correct AnswerverifiedShow Answer

Multiple products are generated from the same gene by what mechanism?

Correct AnswerverifiedA

What mechanism may explain the difference in symptoms in Prader-Willi and Angelman syndromes?

Correct AnswerverifiedShow Answer

The loop of transfer RNA that interacts with the codon on mRNA in translation is called the:

Correct AnswerverifiedD

Which of the following is required for termination of transcription in bacteria?

Correct AnswerverifiedShow Answer

Synthesis of RNA guided by a DNA template is:

Correct AnswerverifiedShow Answer

The most frequently methylated base in vertebrates is:

Correct AnswerverifiedShow Answer

DNA sequences that are involved in the regulation of gene expression are called:

Correct AnswerverifiedShow Answer

Which of the following is involved in termination of transcription in eukaryotes?

Correct AnswerverifiedShow Answer

In the lactose operon, which of the following configurations would result in gene expression?

Correct AnswerverifiedD

The large ribosome subunit in prokaryotes consists of ribosomal proteins and:

Correct AnswerverifiedShow Answer

In transcription, what is the starting material, the ending material, and the major enzyme that catalyzes the process?

Correct AnswerverifiedShow Answer

RNA is degraded by:

Correct AnswerverifiedShow Answer

What is the secondary structure of transfer RNA?

Correct AnswerverifiedShow Answer

Thalassemias arise from changes in what part of the beta-globin gene?

Correct AnswerverifiedShow Answer

When gene expression is regulated by mechanisms other than the interaction of cis elements and trans factors, the regulation is called:

Correct AnswerverifiedShow Answer

Which of the following enzymes performs transcription in bacteria?

Correct AnswerverifiedShow Answer

Which of the following would prevent transcription of the lactose operon?

Correct AnswerverifiedShow Answer

Genomic imprinting is accomplished primarily through:

Correct AnswerverifiedShow Answer

Which of the following types of RNA is directly involved in removing introns from RNA in eukaryotes?

Correct AnswerverifiedShow Answer

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D

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