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In familial hypercholesterolemia, individuals with two abnormal alleles die of heart attacks in childhood, those with only one abnormal allele typically die as young adults, and those with two normal alleles have normal life expectancies.This exemplifies


A) penetrance.
B) codominance.
C) pleiotropy.
D) complete dominance.
E) incomplete dominance.

F) A) and D)
G) B) and D)

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A is composed of a granular cluster of eight proteins called with DNA wound around them, plus a short segment of linker DNA.


A) nucleosome; centrosomes
B) nucleosome; histones
C) chromosome; histones
D) chromosome; centromeres
E) centromere; chromatin

F) A) and E)
G) A) and B)

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The stage at which chromosomes aggregate along the equator of a cell is


A) prophase.
B) metaphase.
C) anaphase.
D) telophase.
E) interphase.

F) A) and B)
G) C) and D)

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Which of these processes occurs during a cell's first gap (G1) phase?


A) DNA is semiconservatively replicated.
B) The nuclear envelope breaks down.
C) The cell synthesizes the enzymes that control mitosis.
D) The cell synthesizes proteins and grows.
E) The chromatin condenses into visible chromosomes.

F) A) and C)
G) C) and E)

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DNA is composed of double-ring nitrogenous bases, whereas RNA is composed of single-ring nitrogenous bases.

A) True
B) False

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Cell division is stimulated by and suppressed by .


A) mitosis; cytokinesis
B) mitosis; contact inhibition
C) cell size; cytokinesis
D) growth factors; contact inhibition
E) cell size; contact inhibition

F) A) and B)
G) None of the above

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opens up one segment of the DNA helix during replication, whereas adds complementary free nucleotides to the exposed DNA strand.


A) DNA ligase; DNA helicase
B) DNA helicase; DNA polymerase
C) DNA ligase; DNA polymerase
D) DNA helicase; DNA ligase
E) DNA polymerase; DNA ligase

F) A) and B)
G) D) and E)

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This figure shows the DNA structure.What does "E" represent?


A) a nitrogenous base
B) a pyrimidine
C) a purine
D) a nucleotide
E) a fragment of the sugar-phosphate backbone

F) B) and D)
G) A) and D)

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Cytokinesis overlaps with which phase of mitosis?


A) the S phase
B) telophase
C) metaphase
D) prophase
E) interphase

F) None of the above
G) A) and B)

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All of the following participate in DNA replication except


A) DNA.
B) ribosomes.
C) DNA ligase.
D) DNA helicase.
E) DNA polymerase.

F) A) and C)
G) A) and E)

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Since there are no genes coding for carbohydrates, nucleic acids, or lipids, how do cells produce them?


A) Enzymes encoded by genes synthesize these products.
B) Cells are born with all the products they need.
C) Cells absorb these products by endocytosis.
D) Cells import these products from older cells.
E) Cells can produce carbohydrates, nucleic acids, and lipids out of proteins.

F) B) and E)
G) B) and C)

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The alleles possessed by all members of a population collectively are called the


A) species DNA.
B) population DNA.
C) gene pool.
D) chromosomes.
E) genes.

F) A) and B)
G) None of the above

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Chromatin shortens and thickens, coiling into compact rods, during


A) telophase.
B) anaphase.
C) interphase.
D) prophase.
E) metaphase.

F) B) and E)
G) D) and E)

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In the cell cycle, DNA polymerase is most active in phase.


A) S
B) G1
C) G2
D) M
E) G0

F) A) and C)
G) A) and E)

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Naked DNA is called chromatin.

A) True
B) False

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This figure shows translation of mRNA.What does "E" show?


A) a newly synthesized amino acid
B) a newly synthesized polypeptide
C) a newly synthesized nucleic acid
D) mRNA
E) tRNA

F) A) and E)
G) A) and B)

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Hemophilia is caused by a sex-linked recessive allele.This means that


A) women can be carriers but cannot get hemophilia.
B) the gene is found on the Y chromosome.
C) a man can give the allele to his son but not to his daughter.
D) a son who has hemophilia inherited the allele from his mother.
E) a son who has hemophilia inherited the allele from his father.

F) D) and E)
G) B) and E)

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This figure shows translation of mRNA.What does "A" show?


A) the molecule that carries codons
B) the molecule that carries anticodons
C) the molecule that carries base triplets
D) the molecule that carries amino acids
E) the molecule that carries tRNA

F) None of the above
G) B) and D)

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All these are found in the karyotype of a normal human male, except


A) 46 chromosomes.
B) 23 pairs of homologous chromosomes.
C) X and Y chromosomes.
D) 46 chromatids.
E) 92 DNA molecules.

F) B) and C)
G) C) and D)

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The genetic code is the correspondence between the and the that they represent.


A) DNA molecule; 20 amino acids
B) DNA molecule; 64 amino acids
C) mRNA anticodons; 20 amino acids
D) mRNA codons; 64 amino acids
E) mRNA codons; 20 amino acids

F) C) and D)
G) B) and C)

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